Indomethacin blocks the increased conditioned rewarding effects of cocaine induced by repeated social defeat.

It is well established that repeated social defeat stress can induce negative long-term consequences such as increased anxiety-like behavior and enhances the reinforcing effect of psychostimulants in rodents. In the current study, we evaluated how the immune system may play a role in these long-term...

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Bibliographic Details
Main Authors: Carmen Ferrer-Pérez, Tamara Escrivá Martinez, Sandra Montagud-Romero, Raúl Ballestín, Marina D Reguilón, José Miñarro, Marta Rodríguez-Arias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209291