HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism

Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study presents miR-210 as a potential therapeutic option...

Full description

Bibliographic Details
Main Authors: Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao, Wan Zhu, Ning Xu Landén, Mona Ståhle, Jingping Zhang, Mircea Ivan, Raluca Georgiana Maltesen, Ileana Ruxandra Botusan, Neda Rajamand Ekberg, Xiaowei Zheng, Sergiu-Bogdan Catrina
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01495-y