Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism

Mitophagy (mitochondrial autophagy) in hepatocytes is an essential quality control mechanism that removes for lysosomal digestion damaged, effete and superfluous mitochondria. Mitophagy has distinct variants. In type 1 mitophagy, typical of nutrient deprivation, cup-shaped sequestration membranes (p...

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Bibliographic Details
Main Authors: John J. Lemasters, Zhi Zhong
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-09-01
Series:Liver Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568418300345