Simplified assay for enrichment of primed human Th17 and Tc17 lymphocytes from peripheral blood

Abstract Background Interleukin-17A (IL-17A) is a potent pro-inflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. The production of IL-17A is commonly associated with subsets of CD4+ T cells (Th17) and CD8+ T cells (Tc17). Identifying these subsets based...

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Bibliographic Details
Main Authors: Pradeep K. Dagur, Elena Stansky, Ankit Saxena, Angélique Biancotto, John Philip McCoy
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Translational Medicine Communications
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41231-019-0041-8