Capsaicin and Proton Differently Modulate Activation Kinetics of Mouse Transient Receptor Potential Vanilloid-1 Channel Induced by Depolarization

Capsaicin and Proton Differently Modulate Activation Kinetics of Mouse Transient Receptor Potential Vanilloid-1 Channel Induced by Depolarization

The transient receptor potential vanilloid type 1 (TRPV1) channel is a non-selective cation channel expressed with transient receptor potential ankyrin type 1 (TRPA1) in small and medial size neurons of the dorsal root ganglions and trigeminal ganglions. TRPV1 is activated by capsaicin, thermal stim...

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Bibliographic Details
Main Authors: Kaori Takahashi, Kentaro Araki, Hideo Miyamoto, Rikimaru Shirakawa, Takashi Yoshida, Minoru Wakamori
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
voltage-dependency
patch-clamp techniques
capsaicin
protons
kinetics
TRPV1 channel
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.672157/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.672157/full

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