Signal response sensitivity in the yeast mitogen-activated protein kinase cascade.

The yeast pheromone response pathway is a canonical three-step mitogen activated protein kinase (MAPK) cascade which requires a scaffold protein for proper signal transduction. Recent experimental studies into the role the scaffold plays in modulating the character of the transduced signal, show tha...

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Bibliographic Details
Main Authors: Craig J Thalhauser, Natalia L Komarova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909145?pdf=render