Transcriptional Regulation of Acyl-CoA:Glycerol-<i>sn</i>-3-Phosphate Acyltransferases

Transcriptional Regulation of Acyl-CoA:Glycerol-<i>sn</i>-3-Phosphate Acyltransferases

Acyl-CoA:glycerol-<i>sn</i>-3-phosphate acyltransferase (GPAT) is an enzyme responsible for the rate-limiting step in the synthesis of glycerophospholipids and triacylglycerol (TAG). The enzymes of mammalian species are classified into four isoforms; GPAT1 and GPAT2 are localized in the...

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Bibliographic Details
Main Authors: Ken Karasawa, Kazunari Tanigawa, Ayako Harada, Atsushi Yamashita
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
GPAT
TAG
SREBP-1c
PPARγ
insulin resistance
obesity
tumorigenesis
Online Access:https://www.mdpi.com/1422-0067/20/4/964

Internet

https://www.mdpi.com/1422-0067/20/4/964

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