Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!
<p>Abstract</p> <p>Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the play of chance. Reliance on such analyses is likely to be more erroneo...
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| Format: | Article |
| Language: | English |
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BMC
2000-07-01
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| Series: | Current Controlled Trials in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | http://cvm.controlled-trials.com/content/1/1/025 |