Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research

Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research

Abstract Cancer research requires models closely resembling the tumor in the patient. Human tissue cultures can overcome interspecies limitations of animal models or the loss of tissue architecture in in vitro models. However, analysis of tissue slices is often limited to histology. Here, we demonst...

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Bibliographic Details
Main Authors: Susann Haehnel, Kristin Reiche, Dennis Loeffler, Andreas Horn, Conny Blumert, Sven-Holger Puppel, Nicole Kaiser, Felicitas Rapp, Michael Rade, Friedemann Horn, Juergen Meixensberger, Ingo Bechmann, Frank Gaunitz, Karsten Winter
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-56509-5

Internet

https://doi.org/10.1038/s41598-019-56509-5

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