Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling.

by Henry Oppermann, Helene Faust, Ulrike Yamanishi, Jürgen Meixensberger, Frank Gaunitz
Published 2019-01-01

Modulation of GLO1 Expression Affects Malignant Properties of Cells

by Antje Hutschenreuther, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, Gerd Birkenmeier
Published 2016-12-01

Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

by Henry Oppermann, Johannes Dietterle, Katharina Purcz, Markus Morawski, Christian Eisenlöffel, Wolf Müller, Jürgen Meixensberger, Frank Gaunitz
Published 2018-08-01

The Chk1 inhibitor SAR-020106 sensitizes human glioblastoma cells to irradiation, to temozolomide, and to decitabine treatment

by Ina Patties, Sonja Kallendrusch, Lisa Böhme, Eva Kendzia, Henry Oppermann, Frank Gaunitz, Rolf-Dieter Kortmann, Annegret Glasow
Published 2019-10-01

Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research

by Susann Haehnel, Kristin Reiche, Dennis Loeffler, Andreas Horn, Conny Blumert, Sven-Holger Puppel, Nicole Kaiser, Felicitas Rapp, Michael Rade, Friedemann Horn, Juergen Meixensberger, Ingo Bechmann, Frank Gaunitz, Karsten Winter
Published 2019-12-01

Phenotypic Screen Identifies a Small Molecule Modulating ERK2 and Promoting Stem Cell Proliferation

by Chang Yin, Chang Yin, Temesgen Fufa, Temesgen Fufa, Gayathri Chandrasekar, Gayathri Chandrasekar, Madhu Aeluri, Madhu Aeluri, Verina Zaky, Shaimaa Abdelhady, Antonio B. Rodríguez, Johan Jakobsson, Farzaneh Shahin Varnoosfaderani, Jayashri Mahalingam, Jianping Liu, Olle Larsson, Outi Hovatta, Frank Gaunitz, Anita Göndör, Michael Andäng, Satish S. Kitambi
Published 2017-10-01

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

by Gayane Hrachia Buniatian, Ralf Weiskirchen, Thomas S. Weiss, Ute Schwinghammer, Martin Fritz, Torgom Seferyan, Barbara Proksch, Michael Glaser, Ali Lourhmati, Marine Buadze, Erawan Borkham-Kamphorst, Frank Gaunitz, Christoph H. Gleiter, Thomas Lang, Elke Schaeffeler, Roman Tremmel, Holger Cynis, William H. Frey, Rolf Gebhardt, Scott L. Friedman, Wolfgang Mikulits, Matthias Schwab, Lusine Danielyan
Published 2020-02-01