Diversity of Clinically Relevant Outcomes Resulting from Hypofractionated Radiation in Human Glioma Stem Cells Mirrors Distinct Patterns of Transcriptomic Changes

Diversity of Clinically Relevant Outcomes Resulting from Hypofractionated Radiation in Human Glioma Stem Cells Mirrors Distinct Patterns of Transcriptomic Changes

Hypofractionated radiotherapy is the mainstay of the current treatment for glioblastoma. However, the efficacy of radiotherapy is hindered by the high degree of radioresistance associated with glioma stem cells comprising a heterogeneous compartment of cell lineages differing in their phenotypic cha...

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Bibliographic Details
Main Authors: Darius Kalasauskas, Maxim Sorokin, Bettina Sprang, Alhassan Elmasri, Sina Viehweg, Gabriela Salinas, Lennart Opitz, Margret Rave-Fraenk, Walter Schulz-Schaeffer, Sven Reiner Kantelhardt, Alf Giese, Anton Buzdin, Ella L. Kim
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
glioblastoma
glioma stem cells
hypofractionated radiation
radioresistance
Online Access:https://www.mdpi.com/2072-6694/12/3/570

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https://www.mdpi.com/2072-6694/12/3/570

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