Preparation and Characterization of PEG4000 Palmitate/PEG8000 Palmitate-Solid Dispersion Containing the Poorly Water-Soluble Drug Andrographolide

Solid dispersion (SD) is the effective approach to improve the dissolution rate and bioavailability of class II drugs with low water solubility and high tissue permeability in the Biopharmaceutics Classification System. This study investigated the effects of polyethylene glycol (PEG) molecular weigh...

Full description

Bibliographic Details
Main Authors: Qingyun Zeng, Liquan Ou, Guowei Zhao, Ping Cai, Zhenggen Liao, Wei Dong, Xinli Liang
Format: Article
Language:English
Published: Hindawi-Wiley 2020-01-01
Series:Advances in Polymer Technology
Online Access:http://dx.doi.org/10.1155/2020/4239207