Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor.

The Varicella Zoster Virus (VZV) is a ubiquitous human alpha-herpesvirus that is the causative agent of chicken pox and shingles. Although an attenuated VZV vaccine (v-Oka) has been widely used in children in the United States, chicken pox outbreaks are still seen, and the shingles vaccine only redu...

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Bibliographic Details
Main Authors: Zhen Zhang, Anca Selariu, Charles Warden, Grace Huang, Ying Huang, Oluleke Zaccheus, Tong Cheng, Ningshao Xia, Hua Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2895648?pdf=render