Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells

Lipid-derived free radicals were detected by electron paramagnetic resonance (EPR) spectrometry when cultured endothelial cells attached to Cytodex beads were exposed to iron-induced oxidant stress in the presence of the spin trap alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN). Radical adduct...

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Bibliographic Details
Main Authors: L S Alexander-North, J A North, K P Kiminyo, G R Buettner, A A Spector
Format: Article
Language:English
Published: Elsevier 1994-10-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520397728