Homozygous of MRP4 Gene rs1751034 C Allele Is Related to Increased Risk of Intravenous Immunoglobulin Resistance in Kawasaki Disease

Homozygous of MRP4 Gene rs1751034 C Allele Is Related to Increased Risk of Intravenous Immunoglobulin Resistance in Kawasaki Disease

Background: Kawasaki disease (KD) is a systemic vasculitis in childhood, which mainly causes damage to coronary arteries, and intravenous immunoglobulin (IVIG) is the initial therapy. IVIG resistance increased risk of coronary complication in KD. And genetic background is involved in the occurrence...

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Bibliographic Details
Main Authors: Yanfei Wang, Yufen Xu, Ping Huang, Di Che, Zhouping Wang, Xijing Huang, Xiaofei Xie, Wei Li, Li Zhang, Xiaoqiong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
coronary artery lesion
rs1751034
multi-drug resistance protein 4
intravenous immunoglobulin resistance
Kawasaki disease
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.510350/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.510350/full

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