Solubility enhancement of glimperide: Development of solid dispersion by solvent melt method, characterization and dosage form development

Solubility enhancement of glimperide: Development of solid dispersion by solvent melt method, characterization and dosage form development

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The aim of the present work was to develop immediate release dosage form of the solid dispersion of glimperide (GLIM) for potential enhancement in the bioavailability. The solid dispersions of GLIM were prepared with PEG6000, PVP K30 and Poloxamer 188, in 1:1, 1:3 and 1:5 %w/w ratio by using solvent...

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Bibliographic Details
Main Authors: Kamla Pathak, Suchitra Kaushik
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2017-05-01
Series:Pharmaceutical and Biomedical Research
Subjects:
glimperide
solid dispersion
solvent wetting method
solvent melt method
immediate release tablet
Online Access:http://pbr.mazums.ac.ir/article-1-181-en.html

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http://pbr.mazums.ac.ir/article-1-181-en.html

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