ZFR coordinates crosstalk between RNA decay and transcription in innate immunity

Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.

Bibliographic Details
Main Authors: Nazmul Haque, Ryota Ouda, Chao Chen, Keiko Ozato, J. Robert Hogg
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03326-5