Discovery of Bioactive Indole-Diketopiperazines from the Marine-Derived Fungus <i>Penicillium brasilianum</i> Aided by Genomic Information

Discovery of Bioactive Indole-Diketopiperazines from the Marine-Derived Fungus <i>Penicillium brasilianum</i> Aided by Genomic Information

Identification and analysis of the whole genome of the marine-derived fungus <i>Penicillium brasilianum</i> HBU-136 revealed the presence of an interesting biosynthetic gene cluster (BGC) for non-ribosomal peptide synthetases (NRPS), highly homologous to the BGCs of indole-diketopiperazi...

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Bibliographic Details
Main Authors: Ya-Hui Zhang, Ce Geng, Xing-Wang Zhang, Hua-Jie Zhu, Chang-Lun Shao, Fei Cao, Chang-Yun Wang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Marine Drugs
Subjects:
biosynthetic gene cluster (BGC)
indole-diketopiperazine
<i>Penicillium brasilianum</i>
cytotoxicities
Online Access:https://www.mdpi.com/1660-3397/17/9/514

Internet

https://www.mdpi.com/1660-3397/17/9/514

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