O2 level controls hematopoietic circulating progenitor cells differentiation into endothelial or smooth muscle cells.

BACKGROUND:Recent studies showed that progenitor cells could differentiate into mature vascular cells. The main physiological factors implicated in cell differentiation are specific growth factors. We hypothesized that simply by varying the oxygen content, progenitor cells can be differentiated eith...

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Bibliographic Details
Main Authors: Nicolas Berthelemy, Halima Kerdjoudj, Pierre Schaaf, Christine Prin-Mathieu, Patrick Lacolley, Jean-François Stoltz, Jean-Claude Voegel, Patrick Menu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2678195?pdf=render