Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway

Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway

Summary: Although stressful events predispose individuals to psychiatric disorders, such as depression, not all people who undergo a stressful life experience become depressed, suggesting that gene-environment interactions (GxE) determine depression risk. The ventral hippocampus (vHPC) plays key rol...

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Bibliographic Details
Main Authors: Yusuke Sakai, Haiyan Li, Hiromichi Inaba, Yuki Funayama, Erina Ishimori, Ayako Kawatake-Kuno, Hirotaka Yamagata, Tomoe Seki, Teruyuki Hobara, Shin Nakagawa, Yoshifumi Watanabe, Susumu Tomita, Toshiya Murai, Shusaku Uchida
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Behavioral neuroscience
Molecular neuroscience
Cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004727

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http://www.sciencedirect.com/science/article/pii/S2589004221004727

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