Progression of Large Lymphoma Is Significantly Impeded with a Combination of Gemcitabine Chemotherapy and Dendritic Cells Intra-Tumor Vaccination.

Relapsed, refractory lymphoma remains to be a challenge and lacks efficient treatment. Some tumor cells escape from treatment, become resistant to chemotherapeutic agents, and rapidly regenerate into large tumors. Lymphoma cells induce accumulation of Gr-1(+-)CD11b(+) myeloid derived suppressor cell...

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Bibliographic Details
Main Authors: Xue-Jun Zhu, Zhong-Fa Yang, Jin-Yong Zhou, Li Liu, Xue-Mei Sun, Zhen-Fang Fan, Shou-You Hu, Yu-Chao Chen, Wei-Xia Li, Meng Cao, Li-Xin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4504496?pdf=render