Human kinetochores are swivel joints that mediate microtubule attachments

Chromosome segregation is a mechanical process that requires assembly of the mitotic spindle – a dynamic microtubule-based force-generating machine. Connections to this spindle are mediated by sister kinetochore pairs, that form dynamic end-on attachments to microtubules emanating from opposite spin...

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Bibliographic Details
Main Authors: Chris A Smith, Andrew D McAinsh, Nigel J Burroughs
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/16159