PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

The aims of the present study were to establish optimal doses and provide an alternate COPD for florfenicol against Streptococcus suis based on pharmacokinetic-pharmacodynamic integration modeling. The recommended dose (30 mg/kg b.w.) were administered in healthy pigs through intramuscular and intra...

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Bibliographic Details
Main Authors: Zhixin Lei, Qianying Liu, Shuaike Yang, Bing Yang, Haseeb Khaliq, Kun Li, Saeed Ahmed, Abdul Sajid, Bingzhou Zhang, Pin Chen, Yinsheng Qiu, Jiyue Cao, Qigai He
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
florfenicol
Streptococcus suis
optimal dosages
pharmacokinetic
pharmacodynamic
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00002/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00002/full

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