Frequency and prognostic significant of CYP3A4-A-290G polymorphism in acute myeloid leukemia

Cytochrome P450 3A4 (CYP3A4) is the most plentiful cytochrome P450 in adult human liver and small intestine and is responsible for detoxification of more than 50% of drugs in addition to the metabolic deactivation and metabolism of many carcinogens. Polymorphism of CYP3A4-A-290G considered the only...

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Bibliographic Details
Main Authors: Gamal T. Ali, Nevin M. Al-azhary, Doha A. Mokhtar
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Advanced Research
Subjects:
AML
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123213001343