The Molecular Mechanisms of Zinc Neurotoxicity and the Pathogenesis of Vascular Type Senile Dementia

The Molecular Mechanisms of Zinc Neurotoxicity and the Pathogenesis of Vascular Type Senile Dementia

Zinc (Zn) is an essential trace element that is abundantly present in the brain. Despite its importance in normal brain functions, excess Zn is neurotoxic and causes neurodegeneration following transient global ischemia and plays a crucial role in the pathogenesis of vascular-type dementia (VD). We...

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Bibliographic Details
Main Authors: Masahiro Kawahara, Dai Mizuno
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
Zinc
carnosine
histidine
vascular-type dementia
Online Access:http://www.mdpi.com/1422-0067/14/11/22067

Internet

http://www.mdpi.com/1422-0067/14/11/22067

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