WNT5A from the fetal liver vascular niche supports human fetal liver hematopoiesis

WNT5A from the fetal liver vascular niche supports human fetal liver hematopoiesis

Abstract The human fetal liver is a critical organ for prenatal hematopoiesis, the study of which offers insights into niche signals that regulate the fates of hematopoietic stem and progenitor cells (HSPCs) during fetal development. Here, we demonstrate that human fetal liver endothelium uniquely s...

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Bibliographic Details
Main Authors: Yoon Jung Choi, Adam M. Heck, Brian J. Hayes, Daniel Lih, Samuel G. Rayner, Brandon Hadland, Ying Zheng
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Stem Cell Research & Therapy
Subjects:
Fetal liver endothelium
WNT5A
Organ-specific
Hematopoiesis
Online Access:https://doi.org/10.1186/s13287-021-02380-z

Internet

https://doi.org/10.1186/s13287-021-02380-z

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