Treatment of pustular psoriasis with anakinra: a statistical analysis plan for stage 1 of an adaptive two-staged randomised placebo-controlled trial

Abstract Background Palmoplantar pustulosis (PPP) is a rare, chronic inflammatory skin disease. It is known to affect quality of life at a level comparable to that from major medical and psychiatric illness, yet current treatment options are remarkably limited. Recent evidence however suggests that...

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Bibliographic Details
Main Authors: Suzie Cro, Catherine Smith, Rosemary Wilson, Victoria Cornelius
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-2914-y