Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerization

Abstract Phosphatidylinositol-4,5-bisphosphate (PIP2), one of the key phospholipids, directly interacts with several membrane and cytosolic proteins at neuronal plasma membranes, leading to changes in neuronal properties including the feature and surface expression of ionotropic receptors. Although...

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Bibliographic Details
Main Authors: Su-Jeong Kim, Min-Jae Jeong, Hee-Jung Jo, Jung Hoon Jung, Bong-Kiun Kaang, Yun-Beom Choi, Joung-Hun Kim
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03520-3