Identification of functional lipid metabolism biomarkers of brown adipose tissue aging

Objective: Aging is accompanied by loss of brown adipocytes and a decline in their thermogenic potential, which may exacerbate the development of adiposity and other metabolic disorders. Presently, only limited evidence exists describing the molecular alterations leading to impaired brown adipogenes...

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Main Authors: Sabrina Gohlke, Vyacheslav Zagoriy, Alvaro Cuadros Inostroza, Michaël Méret, Carola Mancini, Lukasz Japtok, Fabian Schumacher, Doreen Kuhlow, Antonia Graja, Heike Stephanowitz, Markus Jähnert, Eberhard Krause, Andreas Wernitz, Klaus-Jürgen Petzke, Annette Schürmann, Burkhard Kleuser, Tim J. Schulz
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818311918