Striatal molecular signature of subchronic subthalamic nucleus high frequency stimulation in parkinsonian rat.

This study addresses the molecular mechanisms underlying the action of subthalamic nucleus high frequency stimulation (STN-HFS) in the treatment of Parkinson's disease and its interaction with levodopa (L-DOPA), focusing on the striatum. Striatal gene expression profile was assessed in rats wit...

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Bibliographic Details
Main Authors: Sylviane Lortet, Emilie Lacombe, Nicolas Boulanger, Pascal Rihet, Catherine Nguyen, Lydia Kerkerian-Le Goff, Pascal Salin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3617149?pdf=render