Modulating transcription through development of semi-synthetic yeast core promoters.

Altering gene expression regulation by promoter engineering is a very effective way to fine-tune heterologous pathways in eukaryotic hosts. Typically, pathway building approaches in yeast still use a limited set of long, native promoters. With the today's introduction of longer and more complex...

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Bibliographic Details
Main Authors: Thomas Decoene, Sofie L De Maeseneire, Marjan De Mey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224476