Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission

Cellular signalling networks provide information to the cell, but the trade-off between accuracy of information transfer and energetic cost of doing so has not been assessed. Here, the authors investigate a MAPK signalling cascade in budding yeast and find that information is maximised per unit ener...

Full description

Bibliographic Details
Main Authors: Alexander Anders, Bhaswar Ghosh, Timo Glatter, Victor Sourjik
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17276-4