The host response in critically ill sepsis patients on statin therapy: a prospective observational study

Abstract Background Statins can exert pleiotropic anti-inflammatory, vascular protective and anticoagulant effects, which in theory could improve the dysregulated host response during sepsis. We aimed to determine the association between prior statin use and host response characteristics in critical...

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Bibliographic Details
Main Authors: Maryse A. Wiewel, Brendon P. Scicluna, Lonneke A. van Vught, Arie J. Hoogendijk, Aeilko H. Zwinderman, René Lutter, Janneke Horn, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll
Format: Article
Language:English
Published: SpringerOpen 2018-01-01
Series:Annals of Intensive Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13613-017-0349-3