A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells

Summary: The role of maternal and embryonic leucine zipper kinase (MELK) in cancer cell proliferation has been contentious, with recent studies arriving at disparate conclusions. We investigated the in vitro dependency of cancer cells on MELK under a range of assay conditions. Abrogation of MELK exp...

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Bibliographic Details
Main Authors: Yubao Wang, Ben B. Li, Jing Li, Thomas M. Roberts, Jean J. Zhao
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301743