An Immunological Stairway to Severe Tissue Complication Assembly in Bothrops atrox Snakebites

Snakebites are a serious public health problem and, in the Amazon, the Bothrops atrox snake is the most frequent cause of envenomation. B. atrox venom (BaV) causes pathophysiological changes with intense, local inflammatory processes, such as severe tissue complication (STC). However, mechanisms ass...

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Main Authors: Hiochelson Najibe Santos Ibiapina, Allyson Guimarães Costa, Jacqueline Almeida Gonçalves Sachett, Iran Mendonça Silva, Andréa Monteiro Tarragô, Juliana Costa Ferreira Neves, Marllon Wendell Athaydes Kerr, Monique Freire Santana, Olindo Assis Martins-Filho, Marcus Vinícius Guimarães Lacerda, Luiz Carlos Lima Ferreira, Adriana Malheiro, Wuelton Marcelo Monteiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01882/full