A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Glioblastoma in adults, and medulloblastoma and pineoblastoma that mainly affect children, are aggressive brain tumors. The survival for patients with glioblastoma remains dismal. While the cure rate for medulloblastoma exceeds 70%, this figure has stagnated over the past few decades and survivors s...

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Bibliographic Details
Main Authors: Raelene Endersby, Jacqueline Whitehouse, Hilary Hii, Sameer A. Greenall, Terrance G. Johns, Nicholas G. Gottardo
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617305705