MicroRNA-124 Overexpression in Schwann Cells Promotes Schwann Cell-Astrocyte Integration and Inhibits Glial Scar Formation Ability

MicroRNA-124 Overexpression in Schwann Cells Promotes Schwann Cell-Astrocyte Integration and Inhibits Glial Scar Formation Ability

Schwann cell (SC) transplantation is a promising approach for the treatment of spinal cord injury (SCI); however, SC grafts show a low migratory capacity within the astrocytic environment, which inevitably hampers their therapeutic efficacy. The purpose of this study was to explore mechanisms to mod...

Full description

Bibliographic Details
Main Authors: Zhijun Li, Yifei Yu, Juanjuan Kang, Yangyang Zheng, Jinying Xu, Kan Xu, Kun Hou, Yi Hou, Guangfan Chi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spinal cord injury
Schwann cell
microRNA-124
astrocyte
boundary
integration
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00144/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00144/full

Similar Items