Periodicity and dosage optimization of an RNAi model in eukaryotes cells
Abstract Background As a highly efficient and specific gene regulation technology, RNAi has broad application fields and good prospects. The effect of RNAi enhances as the dosage of siRNA increases, while an exorbitant siRNA dosage will inhibit the RNAi effect. So it is crucial to formulate a dose-e...
Main Authors: | Tongle Ma, Yongzhen Pei, Changguo Li, Meixia Zhu |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-06-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-2925-z |
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