Natural killer cell signal integration balances synapse symmetry and migration.

Natural killer (NK) cells discern the health of other cells by recognising the balance of activating and inhibitory ligands expressed by each target cell. However, how the integration of activating and inhibitory signals relates to formation of the NK cell immune synapse remains a central question i...

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Bibliographic Details
Main Authors: Fiona J Culley, Matthew Johnson, J Henry Evans, Sunil Kumar, Rupert Crilly, Juan Casasbuenas, Tim Schnyder, Maryam Mehrabi, Mahendra P Deonarain, Dmitry S Ushakov, Veronique Braud, Günter Roth, Roland Brock, Karsten Köhler, Daniel M Davis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19636352/?tool=EBI