Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Among the epigenetic alterations occurring in cancer, DNA hypermethylation and histone hypoacetylation are the focus of intense research because their pharmacological inhibition has shown to produce antineoplastic activity in a varie...

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Main Authors: Candelaria Myrna, Gonzalez-Fierro Aurora, Trejo-Becerril Catalina, Taja-Chayeb Lucia, Segura-Pacheco Blanca, Rangel-Lopez Edgar, Carrasco-Legleu Claudia, Perez-Cardenas Enrique, Perez-Plasencia Carlos, Chavez-Blanco Alma, Cabrera Gustavo, Duenas-Gonzalez Alfonso
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/6/1/2