Impact of frontal white matter hyperintensity on instrumental activities of daily living in elderly women with Alzheimer disease and amnestic mild cognitive impairment.

BACKGROUND:Instrumental activities of daily living (IADL) start to decline during the progression of amnestic mild cognitive impairment (aMCI) to Alzheimer disease (AD). Cognitive and physical decline are involved in the loss of functional independence. However, little is known about AD-related neur...

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Bibliographic Details
Main Authors: Noriko Ogama, Takashi Sakurai, Toshiharu Nakai, Shumpei Niida, Naoki Saji, Kenji Toba, Hiroyuki Umegaki, Masafumi Kuzuya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333806?pdf=render