Pharmacokinetics of Tedizolid and Pseudoephedrine Administered Alone or in Combination in Healthy Volunteers

Pharmacokinetics of Tedizolid and Pseudoephedrine Administered Alone or in Combination in Healthy Volunteers

Therapeutic doses of tedizolid phosphate, an oxazolidinone antibiotic, lack monoamine oxidase inhibition in vivo, potentially resulting in an improved safety profile versus other oxazolidinones. This randomized, double-blind, placebo-controlled, 2-period, 2-sequence, crossover, phase 1 study (NCT015...

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Bibliographic Details
Main Authors: Shawn Flanagan, Sonia L. Minassian, Philippe Prokocimer
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Journal of Clinical Medicine
Subjects:
antibiotics
drug interactions
oxazolidinone
infectious disease
acute bacterial skin infections
pharmacokinetics
Online Access:http://www.mdpi.com/2077-0383/7/6/150

Internet

http://www.mdpi.com/2077-0383/7/6/150

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