Assessing neuraxial microstructural changes in a transgenic mouse model of early stage Amyotrophic Lateral Sclerosis by ultra‐high field MRI and diffusion tensor metrics

Abstract Objective Cell structural changes are one of the main features observed during the development of amyotrophic lateral sclerosis (ALS). In this work, we propose the use of diffusion tensor imaging (DTI) metrics to assess specific ultrastructural changes in the central nervous system during t...

Full description

Bibliographic Details
Main Authors: Rodolfo G. Gatto, Carina Weissmann, Manish Amin, Ariel Finkielsztein, Ronen Sumagin, Thomas H. Mareci, Osvaldo D. Uchitel, Richard L. Magin
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Animal Models and Experimental Medicine
Subjects:
Online Access:https://doi.org/10.1002/ame2.12112