Integrative genomic and transcriptomic analysis of genetic markers in Dupuytren’s disease

Integrative genomic and transcriptomic analysis of genetic markers in Dupuytren’s disease

Abstract Background Dupuytren’s disease (DD) is a fibroproliferative disorder characterized by thickening and contracting palmar fascia. The exact pathogenesis of DD remains unknown. Results In this study, we identified co-expressed gene set (DD signature) consisting of 753 genes via weighted gene c...

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Bibliographic Details
Main Authors: Junghyun Jung, Go Woon Kim, Byungjo Lee, Jong Wha J. Joo, Wonhee Jang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Medical Genomics
Subjects:
Dupuytren’s disease
Unfolded protein response (UPR)
Endoplasmic reticulum (ER) stress
Multiple-phenotype analysis
trans-regulatory hotspots
ZFP57 zinc finger protein
Online Access:http://link.springer.com/article/10.1186/s12920-019-0518-3

Internet

http://link.springer.com/article/10.1186/s12920-019-0518-3

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