HIV Rev-isited

The human immunodeficiency virus type 1 (HIV-1) proteome is expressed from alternatively spliced and unspliced genomic RNAs. However, HIV-1 RNAs that are not fully spliced are perceived by the host machinery as defective and are retained in the nucleus. During late infection, HIV-1 bypasses this reg...

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Bibliographic Details
Main Authors: Catherine Toni-Sue Truman, Aino Järvelin, Ilan Davis, Alfredo Castello
Format: Article
Language:English
Published: The Royal Society 2020-12-01
Series:Open Biology
Subjects:
hiv
rev
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200320