Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity

<p>Abstract</p> <p>Background</p> <p><it>HER2 </it>gene copy status, and concomitant administration of trastuzumab (Herceptin), remains one of the best examples of targeted cancer therapy based on understanding the genomic etiology of disease. However, newly...

Full description

Bibliographic Details
Main Authors: Zadeh Soheila, Dzidic Natasha, Tirtorahardjo Budi, Lytvak Irina, Yeh I-Tien, Gunn Shelly, Kim Jaeweon, McCaskill Chris, Lim Lony, Gorre Mercedes, Mohammed Mansoor
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/396