The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer

The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common cause of cancer related death in the world. Cisplatin and carboplatin are the most commonly used cytotoxic chemotherapeutic agents to treat the disease. These agents, usually combined with drugs such as gemcitabine or pemetrexed, induce objective...

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Bibliographic Details
Main Authors: Steven G. Gray, Kenneth J. O’Byrne, Martin P. Barr
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Cancers
Subjects:
epigenetics
histone
post-translational modification
DNA methylation
epigenetic modifiers
cisplatin
NSCLC
Online Access:http://www.mdpi.com/2072-6694/3/1/1426/

Internet

http://www.mdpi.com/2072-6694/3/1/1426/

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