Genotype-Dependent Difference in 5-HT2C Receptor-Induced Hypolocomotion: Comparison with 5-HT2A Receptor Functional Activity

In the present study behavioral effects of the 5-HT2C serotonin receptor were investigated in different mouse strains. The 5-HT2C receptor agonist MK-212 applied intraperitoneally induced significant dose-dependent reduction of distance traveled in the open field test in CBA/Lac mice. This effect wa...

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Bibliographic Details
Main Authors: Darya V. Bazovkina, Elena M. Kondaurova, Vladimir S. Naumenko, Evgeni Ponimaskin
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/846589