Serum klotho concentrations inversely correlate with the severity of nailfold capillaroscopic patterns in patients with systemic sclerosis

Klotho is a transmembrane and soluble glycoprotein that governs vascular integrity. Previous studies have demonstrated reduced serum klotho concentrations in patients with systemic sclerosis (SSc), and it is known that klotho deficiency can impair the healing of digital ulcers related to microvesse...

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Bibliographic Details
Main Authors: R. Talotta, F. Rigamonti, T. Letizia, S. Bongiovanni, M.C. Ditto, M. Antivalle, S. Santandrea, F. Atzeni, T. Vago, P. Sarzi-Puttini
Format: Article
Language:English
Published: PAGEPress Publications 2019-04-01
Series:Reumatismo
Subjects:
Online Access:https://www.reumatismo.org/index.php/reuma/article/view/1129