SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

Abstract Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in critically ill patients. A better comprehension of SARS-CoV-2-induced monocyte death is essential for the identification of therapies c...

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Bibliographic Details
Main Authors: André C. Ferreira, Vinicius Cardoso Soares, Isaclaudia G. de Azevedo-Quintanilha, Suelen da Silva Gomes Dias, Natalia Fintelman-Rodrigues, Carolina Q. Sacramento, Mayara Mattos, Caroline S. de Freitas, Jairo R. Temerozo, Lívia Teixeira, Eugenio Damaceno Hottz, Ester A. Barreto, Camila R. R. Pão, Lohanna Palhinha, Milene Miranda, Dumith Chequer Bou-Habib, Fernando A. Bozza, Patrícia T. Bozza, Thiago Moreno L. Souza
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00428-w